Past Seminars

Here is the list of our past seminars :


Jean Leon Maitre (GDB, Institut Curie). Biophysics Seminar ESPCI-ENS

Friday 4 November 2016 13:00-14:00 - Amphi Urbain, Ground Floor, Staircase N

Mechanics of blastocyst morphogenesis

During pre-implantation development, the mammalian embryos forms the blastocyst, the structure that will implant into the uterus. Consisting of an epithelium enveloping a fluid-filled cavity and the inner cell mass, the blastocyst is sculpted by a succession of morphogenetic events. These deformations result from the changes in the forces and mechanical properties of the tissue composing the embryo. Using microaspiration, live-imaging, genetics and theoretical modelling, we study the biophysical and cellular changes leading to the formation of the blastocyst. In particular, we uncover the crucial role of acto-myosin myosin contractility, which generates periodic waves of contractions, compacts the embryo, controls the position of cells within the embryo and influences fate specification.






Séminaires récents  (0)


Jean Leon Maitre (GDB, Institut Curie). Biophysics Seminar ESPCI-ENS

Friday 4 November 2016 13:00-14:00 - Amphi Urbain, Ground Floor, Staircase N

Mechanics of blastocyst morphogenesis

During pre-implantation development, the mammalian embryos forms the blastocyst, the structure that will implant into the uterus. Consisting of an epithelium enveloping a fluid-filled cavity and the inner cell mass, the blastocyst is sculpted by a succession of morphogenetic events. These deformations result from the changes in the forces and mechanical properties of the tissue composing the embryo. Using microaspiration, live-imaging, genetics and theoretical modelling, we study the biophysical and cellular changes leading to the formation of the blastocyst. In particular, we uncover the crucial role of acto-myosin myosin contractility, which generates periodic waves of contractions, compacts the embryo, controls the position of cells within the embryo and influences fate specification.






Archives des anciens séminaires  (42)


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