• Home >
  • Past Seminars

Past Seminars

Here is the list of our past seminars:


Francis Corson (LPS, ENS). Biophysics seminar ESPCI-ENS.

Friday 25 November 2016 from 13:00 to 14:00 - ENS, Room L369, 3rd floor

Positional information and self-organization: how the fly lays out its sense organs

The emergence of spatial patterns in developing multicellular organisms relies on positional cues and cell-cell communication. Drosophila sensory organs have informed a paradigm where these operate in two distinct steps: prepattern factors drive localized proneural activity, then Notch-mediated lateral inhibition singles out neural precursors. Using a combination of experiments and modeling, we show that Notch signaling also organizes the proneural stripes that resolve into rows of sensory bristles on the fly thorax. Patterning, initiated by a gradient of Delta ligand expression, progresses through inhibitory signaling between and within stripes. Thus Notch signaling can support self-organized tissue patterning as a broad prepattern is transduced by cell-cell interactions into a refined arrangement of cellular fates.






Recent seminars  (0)


Francis Corson (LPS, ENS). Biophysics seminar ESPCI-ENS.

Friday 25 November 2016 from 13:00 to 14:00 - ENS, Room L369, 3rd floor

Positional information and self-organization: how the fly lays out its sense organs

The emergence of spatial patterns in developing multicellular organisms relies on positional cues and cell-cell communication. Drosophila sensory organs have informed a paradigm where these operate in two distinct steps: prepattern factors drive localized proneural activity, then Notch-mediated lateral inhibition singles out neural precursors. Using a combination of experiments and modeling, we show that Notch signaling also organizes the proneural stripes that resolve into rows of sensory bristles on the fly thorax. Patterning, initiated by a gradient of Delta ligand expression, progresses through inhibitory signaling between and within stripes. Thus Notch signaling can support self-organized tissue patterning as a broad prepattern is transduced by cell-cell interactions into a refined arrangement of cellular fates.






Seminar archive  (219)


Top



See also...

Register our newsletter

Justo grâvida vel facîlisis çurcus porta non dapidûs c’est dictumst sét vel pulvîar vulputate orci sét litoré, aliquet classé lacus facîlisis pérès £at (...) 

> More...

Practical Informations

Our weekly biophysics seminar is co-organized with colleagues at ENS and ESPCI. The audience is mainly composed of physicists with a deep (...) 

> More...